BOUŘ, Petr, Hana NAVRÁTILOVÁ, Marie URBANOVÁ, Vladimír SETNIČKA and Karel VOLKA. (3R,4S)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: Conformation and structure monitoring by vibrational circular dichroism. Journal of Organic Chemistry. 2002, vol. 67, No 1, p. 161-168. ISSN 0022-3263.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name (3R,4S)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: Conformation and structure monitoring by vibrational circular dichroism
Authors BOUŘ, Petr (203 Czech Republic, guarantor), Hana NAVRÁTILOVÁ (203 Czech Republic), Marie URBANOVÁ (203 Czech Republic), Vladimír SETNIČKA (203 Czech Republic) and Karel VOLKA (203 Czech Republic).
Edition Journal of Organic Chemistry, 2002, 0022-3263.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10401 Organic chemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.217
RIV identification code RIV/00216224:14310/02:00006398
Organization unit Faculty of Science
UT WoS 000173151200025
Keywords in English absolute configuration; VCD; piperidines; paroxetine; femoxetine;
Tags absolute configuration, femoxetine, paroxetine, piperidines, VCD
Changed by Changed by: RNDr. Hana Navrátilová, Ph.D., učo 17605. Changed: 14/5/2003 14:36.
Abstract
Absorption and vibrational circular dichroism (VCD) spectra of the title compound, a common intermediate in synthesis of many pharmaceuticals, were measured and analyzed in order to determine its absolute configuration and prevailing conformations.
Links
MSM 143100011, plan (intention)Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů
Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles
PrintDisplayed: 13/10/2024 15:48