J 2002

(3R,4S)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: Conformation and structure monitoring by vibrational circular dichroism

BOUŘ, Petr, Hana NAVRÁTILOVÁ, Marie URBANOVÁ, Vladimír SETNIČKA, Karel VOLKA et. al.

Basic information

Original name

(3R,4S)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: Conformation and structure monitoring by vibrational circular dichroism

Authors

BOUŘ, Petr (203 Czech Republic, guarantor), Hana NAVRÁTILOVÁ (203 Czech Republic), Marie URBANOVÁ (203 Czech Republic), Vladimír SETNIČKA (203 Czech Republic) and Karel VOLKA (203 Czech Republic)

Edition

Journal of Organic Chemistry, 2002, 0022-3263

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10401 Organic chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.217

RIV identification code

RIV/00216224:14310/02:00006398

Organization unit

Faculty of Science

UT WoS

000173151200025

Keywords in English

absolute configuration; VCD; piperidines; paroxetine; femoxetine;
Změněno: 14/5/2003 14:36, RNDr. Hana Navrátilová, Ph.D.

Abstract

V originále

Absorption and vibrational circular dichroism (VCD) spectra of the title compound, a common intermediate in synthesis of many pharmaceuticals, were measured and analyzed in order to determine its absolute configuration and prevailing conformations.

Links

MSM 143100011, plan (intention)
Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů
Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles