Detailed Information on Publication Record
2002
Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
ŽOURKOVÁ, Alexandra and Eva HADAŠOVÁBasic information
Original name
Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
Name in Czech
Paroxetin a vztah mezi CYP2D6, metabolickým stavem a sexuální dysfunkcí
Authors
ŽOURKOVÁ, Alexandra (203 Czech Republic, guarantor) and Eva HADAŠOVÁ (203 Czech Republic)
Edition
Journal of Sex and Marital Therapy, Philadelphia,USA, Taylor and Francis Health Sciences, 2002, 0092-623X
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.551
RIV identification code
RIV/00216224:14110/02:00006445
Organization unit
Faculty of Medicine
UT WoS
000178446900009
Keywords in English
sexual dysfunction; CYP2D6; paroxetine; poor metabolizer
Tags
International impact, Reviewed
Změněno: 24/6/2009 09:23, prof. MUDr. Alexandra Žourková, CSc.
V originále
This article describes the incidence of sexual dysfunction in 30 patients subjected to long-term treatment by paroxetine in dependence on the P 450 CYP 2D6 isoenzyme metabolic status. Measured on the Arizona Sexual Experience Scale (ASEX; McGahuey, Delgado, & Gelenberg, 1999), the incidence of sexual dysfunction inpatients converted to CYP 2D6 poor metabolizers was markedly higher compared with patients who had no history of such conversion, a difference that reached the level of statistical significance. Our article discusses the incidence of sexual dysfunction in connection with reduced CYP 2D6 capacity.
In Czech
Článek studuje Paroxetin a vztah mezi CYP2D6, metabolickým stavem a sexuální dysfunkcí
Links
| NF6159, research and development project |
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