The role of actin cytoskeleton in apoptotic cell death

NERADIL, Jakub, Renata VESELSKÁ, Karel ZITTERBART and Augustin SVOBODA. The role of actin cytoskeleton in apoptotic cell death. In 10th Euroconference on Apoptosis - "Charming to Death". 2002.

Basic information

• Original name: The role of actin cytoskeleton in apoptotic cell death
• Authors: NERADIL, Jakub (203 Czech Republic, guarantor), Renata VESELSKÁ (203 Czech Republic), Karel ZITTERBART (203 Czech Republic) and Augustin SVOBODA (203 Czech Republic).
• Edition: 10th Euroconference on Apoptosis - "Charming to Death" 2002.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/02:00006514
• Organization unit: Faculty of Medicine
• Keywords in English: induced differentiation; apoptosis; actin cytoskeleton; HL-60 cell line; P19 cell line
• Tags: actin cytoskeleton, apoptosis, HL-60 cell line, induced differentiation, P19 cell line

Abstract

Morphology of the actin cytoskeleton during apoptosis associated with the process of induced differentiation was studied on P19 and HL-60 cell lines using transmission electron microscopy, epifluorescence and confocal microscopy. Actin cytoskeleton underwent specific alterations and rearrangements during the apoptotic process. These structural changes are common for the apoptotic cell death, play the active role in the morphological features of apoptosis and they are independent on the course of differentiation associated with apoptosis induction.

Links

• GA304/00/0403, research and development project: Name: Změny cytoskeletu buněk nádorových linií v průběhu indukované apoptózy v závislosti na stádiu diferenciace.

Investor: Czech Science Foundation, Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation