ZELENKOVÁ, Olga, Eva ČEŠKOVÁ, Eva HADAŠOVÁ and Alexandra ŽOURKOVÁ. Zhodnocení dosavadních zkušeností s dynamikou aktivity CYP2D6 (Evaluation of the current experience with the dynamics of CYP2D6 activity). Psychiatrie. Praha: TIGIS s.r.o., 2002, vol. 6, Suppl.1, p. 45. ISSN 1211-7579.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Zhodnocení dosavadních zkušeností s dynamikou aktivity CYP2D6
Name (in English) Evaluation of the current experience with the dynamics of CYP2D6 activity
Authors ZELENKOVÁ, Olga (203 Czech Republic, guarantor), Eva ČEŠKOVÁ (203 Czech Republic), Eva HADAŠOVÁ (203 Czech Republic) and Alexandra ŽOURKOVÁ (203 Czech Republic).
Edition Psychiatrie, Praha, TIGIS s.r.o. 2002, 1211-7579.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/02:00006817
Organization unit Faculty of Medicine
Keywords in English Genetic polymorphism; CYP2D6; psychiatry; enzyme inhibition;
Tags CYP2D6, enzyme inhibition, genetic polymorphism, psychiatry
Tags International impact
Changed by Changed by: prof. MUDr. Alexandra Žourková, CSc., učo 81. Changed: 25/11/2006 10:12.
Abstract
Práce sledovala dynamiku metabolické kapacity CYP2D6 v průběhu 28-denní léčby psychotropními látkami. Bylo potvrzeno, že léčba psychotropiky může vyvolat změnu fenotypu CYP2D6 z extenzivního (EM) na slabý (PM) metabolický fenotyp.
Abstract (in English)
The study followed the dynamics of the metabolic capacity of CYP2D6 during the 28-day treatment with various psychotropic drugs. It was confirmed that the psychopharmacotherapy may change the CYP2D6 phenotype from the extensive (EM) to the poor (PM) metabolic phenotype.
PrintDisplayed: 25/7/2024 23:21