Influence of endocannabinoids anandamide and noladin on mouse leukocyte phagocytosis

VINKLEROVÁ, Jana and Alexandra ŠULCOVÁ. Influence of endocannabinoids anandamide and noladin on mouse leukocyte phagocytosis. Adiktologie. Tišnov: Sdružení SCAN, 2002, vol. 1, suppl. 1, p. 76-77. ISSN 1213-3841.

Basic information

Original name

Influence of endocannabinoids anandamide and noladin on mouse leukocyte phagocytosis

Authors

VINKLEROVÁ, Jana (203 Czech Republic, guarantor) and Alexandra ŠULCOVÁ (203 Czech Republic)

Edition

Adiktologie, Tišnov, Sdružení SCAN, 2002, 1213-3841

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/02:00006892

Organization unit

Faculty of Medicine

Keywords in English

cannabinoids; anandamide; noladin; leukocyte phagocytosis; chemiluminescence; mice

Tags

anandamide, cannabinoids, chemiluminescence, leukocyte phagocytosis, mice, noladin

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Abstract

V originále

The cannabinoids are involved in regulation of immune function. This action can be mediated either through cannabinoid receptors which subtypes CB1 and CB2 have been identified on leukocytes, or by non-receptor mechanism not clearly understood yet. The present study investigated the influence of the endocannabinoids (anandamide, noladin) on the cellular immune function on leukocyte phagocytosis. Phagocytic activity of mouse leukocytes was measured in chemiluminescence (CL) assay using zymosan induction of phagocytosis and luminol potentiated of CL in vitro.