Detailed Information on Publication Record
2002
Differential effects of v-Jun and c-Jun proteins on v-myb-transformed monoblasts
ŠEVČÍKOVÁ, Sabina, Karel SOUČEK, Lukáš KUBALA, Vítězslav BRYJA, Jan ŠMARDA et. al.Basic information
Original name
Differential effects of v-Jun and c-Jun proteins on v-myb-transformed monoblasts
Authors
ŠEVČÍKOVÁ, Sabina (203 Czech Republic), Karel SOUČEK (203 Czech Republic), Lukáš KUBALA (203 Czech Republic), Vítězslav BRYJA (203 Czech Republic) and Jan ŠMARDA (203 Czech Republic, guarantor)
Edition
Cellular and Molecular Life Sciences, Bäsel, Birkhaeuser Verlag, 2002, 1420-682X
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Switzerland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 5.259
RIV identification code
RIV/00216224:14310/02:00006908
Organization unit
Faculty of Science
UT WoS
000179686000014
Keywords in English
v-Myb; Jun; differebtiation; proliferation; retinoic acid; phorbol ester
Změněno: 17/2/2009 08:18, prof. RNDr. Jan Šmarda, CSc.
Abstract
V originále
The line of v-myb-transformed chicken monoblats BM2 can be induced to terminal differentiation using phorbol esters. The fact that Jun proteins are up-regulated in the phorbol ester-treated BM2 cells promptred us to investigate the role of the Jun proteins in regulation of myeloid differentiation. We ectopically expressed v-jun and c-jun in BM2 cells and evaluated their effects on differentiation, proliferation and apoptosis.
Links
| GA301/01/0040, research and development project |
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| MSM 143100008, plan (intention) |
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