J 2002

Effect of methamphetamine and fluoxetine combination on behavioural activity in wistar albino rats

DOSTÁLEK, Miroslav, Jana PISTOVČÁKOVÁ, Jiří SLÍVA and Eva HADAŠOVÁ

Basic information

Original name

Effect of methamphetamine and fluoxetine combination on behavioural activity in wistar albino rats

Name in Czech

Vliv kombinace fluoxetinu a metamfetaminu na behaviorání aktivitu u potkana kmene Wistar

Authors

DOSTÁLEK, Miroslav (203 Czech Republic), Jana PISTOVČÁKOVÁ (703 Slovakia), Jiří SLÍVA (203 Czech Republic) and Eva HADAŠOVÁ (203 Czech Republic, guarantor)

Edition

Bratislavské lekárské listy, Bratislava, Slovak Academic Press, s.r.o. Bratislava, 2002, 0006-9248

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14110/02:00006928

Organization unit

Faculty of Medicine

Keywords in English

fluoxetine; methamphetamine; behaviour; rat

Tags

Změněno: 31/5/2005 10:57, PharmDr. Miroslav Dostálek, Ph.D.

Abstract

ORIG CZ

V originále

Locomotor / exploratory behavioural changes were followed in Wistar rats pretreated with methamphetamine, fluoxetine or their combination. An "open field" (Acti-track, Panlab, Spain) was used as the tracking arena. Methamphetamine significantly increased all measured behavioural parameters while fluoxetine showed inhibitory effects. Pretreatment with combination of these drugs resulted in a more profound inhibition of locomotor activity than in fluoxetine given alone.

In Czech

Locomotor / exploratory behavioural changes were followed in Wistar rats pretreated with methamphetamine, fluoxetine or their combination. An "open field" (Acti-track, Panlab, Spain) was used as the tracking arena. Methamphetamine significantly increased all measured behavioural parameters while fluoxetine showed inhibitory effects. Pretreatment with combination of these drugs resulted in a more profound inhibition of locomotor activity than in fluoxetine given alone.