Involvement of the 5-HT1A receptor subtype in regulation of anxiety-like and aggressive behaviour in mice

NOVÁKOVÁ, Jana, Jana VINKLEROVÁ and Alexandra ŠULCOVÁ. Involvement of the 5-HT1A receptor subtype in regulation of anxiety-like and aggressive behaviour in mice. In Programme and abstracts of the Conference: NEUROSCIENCE IN THE THIRD MILLENIUM (X. International Congress of the Czech and Slovak Society). Častá, Slovak Republic: Czech and Slovak Neurochemical Society, 2002, p. 61.

Basic information

Original name

Involvement of the 5-HT1A receptor subtype in regulation of anxiety-like and aggressive behaviour in mice

Authors

NOVÁKOVÁ, Jana (203 Czech Republic, guarantor), Jana VINKLEROVÁ (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic)

Edition

Častá, Slovak Republic, Programme and abstracts of the Conference: NEUROSCIENCE IN THE THIRD MILLENIUM (X. International Congress of the Czech and Slovak Society), p. 61-61, 2002

Publisher

Czech and Slovak Neurochemical Society

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Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/02:00006945

Organization unit

Faculty of Medicine

Keywords in English

5-HT1A receptor subtype; anxiety; aggression; agonistic behaviour; mice

Tags

5-HT1A receptor subtype, aggression, agonistic behaviour, anxiety, mice

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Abstract

V originále

Using the model of agonistic behviour in mice we evaluated the effect of the selective 5-HT1A receptor ligand S 15535 on paired social interactions of singly-housed male mice with non-aggressive group-housed partners. The study brought the evidence that S 15535 possesses marked antiaggressive effect and less pronounced anxiolytic activity, results resembling those of our earlier testing of other selective 5-HT1A ligands flesinoxane and buspirone.