Detailed Information on Publication Record
2002
A survey of effects of excessive bromide intake on iodine metabolism in the rat
PAVELKA, StanislavBasic information
Original name
A survey of effects of excessive bromide intake on iodine metabolism in the rat
Name in Czech
Přehled účinků nadbytečného příjmu bromidu na metabolismus jodu u potkana
Authors
PAVELKA, Stanislav (203 Czech Republic, guarantor)
Edition
Leipzig, Macro and Trace Elements/Mengen- und Spurenelemente (Anke M., Müller R., Schäfer U., Stoeppler M., eds.) [IF=n.a.], p. 567-574, 8 pp. Agricult., Biological, Environmental, Nutrit., 21, 2002
Publisher
SCHUBERT-Verlag
Other information
Language
English
Type of outcome
Kapitola resp. kapitoly v odborné knize
Field of Study
30202 Endocrinology and metabolism
Country of publisher
Germany
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/02:00007113
Organization unit
Faculty of Science
ISBN
3-929526-73-5
Keywords in English
bromide; iodine; metabolism; rat; thyroid
Tags
Tags
International impact, Reviewed
Změněno: 10/4/2010 14:36, doc. RNDr. Stanislav Pavelka, CSc.
Abstract
V originále
We studied the effects of an increased bromide intake, at different levels of iodine supply to the organism, on various aspects of iodine metabolism in the rat. A reduction of the food intake and consequently of the body weight gain was observed in rats drinking water with the highest bromide concentration (5 g bromide per liter). An increase in the relative weight of the thyroids and a significant decrease in the 24-h uptake of radioiodide by the thyroids were also found in these animals, especially in those fed a research low-iodine diet. The concentration ratio [I]/[Br] in the thyroids proved to be a very sensitive marker of even negligibly increased bromide intake in the rats.
Links
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