D 2002

Effects of high bromide intake on various aspects of iodine metabolism in the rat

PAVELKA, Stanislav, Arnošt BABICKÝ and Miloslav VOBECKÝ

Basic information

Original name

Effects of high bromide intake on various aspects of iodine metabolism in the rat

Authors

PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic) and Miloslav VOBECKÝ (203 Czech Republic)

Edition

Brno, Proceedings, 6th Workshop of Biochemists and Molecular Biologists, p. 60-61, 2 pp. 2002

Publisher

Masaryk University

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/02:00007116

Organization unit

Faculty of Science

ISBN

80-210-2777-0

Keywords in English

bromide; iodine; metabolism; rat; thyroid

Tags

Změněno: 10/1/2009 17:44, doc. RNDr. Stanislav Pavelka, CSc.

Abstract

V originále

We have demonstrated a significant influence of an excessively high bromide intake in adult male and female rats on the kinetics of radioiodide uptake and elimination by the thyroid gland, skin, and mammary glands. From the results of our experiments, we concluded that high bromide levels in the organism of experimental animals could affect their iodine metabolism in two parallel ways: by a decrease in iodide accumulation in the thyroid, and by a rise in iodide excretion from the body by the kidneys.

Links

NJ6109, research and development project
Name: Interference bromidu z životního prostředí s metabolismem jodu ve štítné žláze a dalších tkáních
Investor: Ministry of Health of the CR, Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues