Detailed Information on Publication Record
2003
Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections
RŮŽIČKOVÁ, Vladislava, Roman PANTŮČEK, Petr PETRÁŠ, Jiří DOŠKAŘ, Ivo SEDLÁČEK et. al.Basic information
Original name
Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections
Name in Czech
Molekulární typizace kmenů Staphylococcus aureus produkujících exfoliativní toxiny a podílejících se na epidermolytických infekcích
Authors
RŮŽIČKOVÁ, Vladislava (203 Czech Republic, guarantor), Roman PANTŮČEK (203 Czech Republic), Petr PETRÁŠ (203 Czech Republic), Jiří DOŠKAŘ (203 Czech Republic), Ivo SEDLÁČEK (203 Czech Republic) and Stanislav ROSYPAL (203 Czech Republic)
Edition
International Journal of Medical Microbiology, München, Germany, Urban & Fischer Verlag, 2003, 1438-4221
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Germany
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 2.583
RIV identification code
RIV/00216224:14310/03:00009834
Organization unit
Faculty of Science
UT WoS
000181489500014
Keywords in English
Bacterial Typing Techniques; DNA; Staphylococcus aureus; Exfoliative Toxin; Nucleic Acid Hybridization; Ribotyping; Pulsed Field-Gel Electrophoresis
Tags
Tags
International impact, Reviewed
Změněno: 1/7/2009 18:38, prof. RNDr. Roman Pantůček, Ph.D.
V originále
Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affected by an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted in the determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged impetigo infections.
In Czech
Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affected by an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted in the determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged impetigo infections.
Links
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