Detailed Information on Publication Record
2002
Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis
PAZOUREK, Jiří, Cathrin PERRIN and Luc MASSARTBasic information
Original name
Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis
Authors
PAZOUREK, Jiří (203 Czech Republic, guarantor), Cathrin PERRIN (250 France) and Luc MASSART (250 France)
Edition
Chromatographia, Friedrich Vieweg a synové, 2002, 0009-5893
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10406 Analytical chemistry
Country of publisher
Germany
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.230
RIV identification code
RIV/00216224:14330/02:00007232
Organization unit
Faculty of Informatics
Keywords in English
Capillary electrophoresis; Chiral separation; beta-cyclodextrin; Racemic switch
Změněno: 31/5/2003 15:25, RNDr. JUDr. Vladimír Šmíd, CSc.
Abstract
V originále
A new method of calibration designed for chiral compounds named: Calibration with Self-internal Standard, is suggested. Here, the second enantiomer serves as the internal standard, the total concentration of both enantiomers is known and kept constant. The method is an alternative to the commonly used calibration with an internal standard being a chemically different compound. The applicability of the method is demonstrated on the calibration of propranolol hydrochloride in capillary zone electrophoresis. Statistical characteristics of the method are compared to calibration without an internal standard and with L-tryptophan as internal standard.
Links
| MSM 143100011, plan (intention) |
|