Dvoukomponentni systemy: regulatory odpovedi a prenos signalu u Arabidopsis thaliana

HORÁK, Jakub and Matej LEXA. Dvoukomponentni systemy: regulatory odpovedi a prenos signalu u Arabidopsis thaliana (Two-component systems: response regulators and signal transduction in Arabidopsis thaliana). Biologické listy. Praha: ÚMG AV ČR, 2003, vol. 67, No 4, p. 297-317. ISSN 0366-0486.

Basic information

• Original name: Dvoukomponentni systemy: regulatory odpovedi a prenos signalu u Arabidopsis thaliana
• Name (in English): Two-component systems: response regulators and signal transduction in Arabidopsis thaliana
• Authors: HORÁK, Jakub (203 Czech Republic, guarantor) and Matej LEXA (703 Slovakia).
• Edition: Biologické listy, Praha, ÚMG AV ČR, 2003, 0366-0486.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: Genetics and molecular biology
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/03:00007935
• Organization unit: Faculty of Science
• Keywords in English: two-component system; histidine kinase; histidinkinase domain; receiver domain; response regulator; HPt domain
• Tags: HISTIDINE KINASE, histidinkinase domain, HPt domain, receiver domain, RESPONSE REGULATOR, TWO-COMPONENT SYSTEM
• Tags: Reviewed

Abstract

Klicovym mechanismem pri vnitrobunecnem prenosu signalu je u prokaryotickych i eukaryotickych organismu fosforylace proteinu. Fosforylace His a Asp v dvoukomponentnich systemech (TCS) je dulezitym mechanismem prenosu signalu u prokaryotu, ktery byl nedavno objeven i u vyssich rostlin. U Arabidopsis thaliana odpovida za prenos signalu v etylenove a cytokininove draze. Studium prenosu signalu v TCS nam pomuze lepe pochopit funkci techto dvou hormonu u rostlin. V nasem clanku shrnujeme dosavadni znalosti o TCS u prokaryotu a eukaryotu. Na priklade rostliny Arabidopsis thaliana pak na zaklade publikovanych i vlastnich vysledku predstavujeme podrobne predevsim funkci regulatoru odpovedi a prezentujeme pravdepodobny model fungovani dvoukomponentnich regulacnich obvodu u Arabidopsis.

Abstract (in English)

His-Asp phosphorelay in two-component systems (TCS) comprising a sensor histidine kinase and response regulator plays a key role in the response to environmental stimuli especially in prokaryotes. Similar TCS were recently found to exist in yeast, fungi, Dictyostelium and plants. In Arabidopsis thaliana TCS have been shown to be involved in ethylene and cytokinin signalling. Elucidation of the signalling mechanisms is crucial for understanding the action of two important hormones. In this paper, we summarize the current knowledge about prokaryotic and eukaryotic TCS. Focusing on TCS in Arabidopsis thaliana and surveying the Arabidopsis response regulator (ARR) genes, we have constructed a phylogenetic tree of the ARR family, and derived a probable model for operation of two-component circuits in Arabidopsis.

Links

• GA204/99/D024, research and development project: Name: Funkce homologů bakteriálních regulátorů indukovatelných dusičnany v rostlinách Arabidopsis thaliana

Investor: Czech Science Foundation, The role of nitrate-inducible bacterial response regulator homologs in Arabidopsis thaliana

• LN00A081, research and development project: Name: Signální dráhy u rostlin
• MSM 143100008, plan (intention): Name: Genomy a jejich funkce

Investor: Ministry of Education, Youth and Sports of the CR, Genomes and their functions