| HASOŇ, Stanislav, Jakub DVOŘÁK, František JELEN and Vladimír VETTERL. Electrochemical Detection of Interactions of Echinomycin with DNA at Mercury Film Electrodes (MFE). In Book of Abstracts, US-CZ Workshops on Electrochemical Sensors Prague 2001. Prague: US-CZ Workshop on Electrochemical Sensors Prague, 2001, p. 42. ISBN 80-86238-15-6. |
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@inproceedings{484360,
author = {Hasoň, Stanislav and Dvořák, Jakub and Jelen, František and Vetterl, Vladimír},
address = {Prague},
booktitle = {Book of Abstracts, US-CZ Workshops on Electrochemical Sensors Prague 2001},
keywords = {DNA-echinomycin interaction; electrochemical impedance spectroscopy;EIS; DNA adsorption; mercuiry film electrodes;},
language = {eng},
location = {Prague},
isbn = {80-86238-15-6},
pages = {42-42},
publisher = {US-CZ Workshop on Electrochemical Sensors Prague},
title = {Electrochemical Detection of Interactions of Echinomycin with DNA at Mercury Film Electrodes (MFE).},
year = {2001}
}
TY - JOUR
ID - 484360
AU - Hasoň, Stanislav - Dvořák, Jakub - Jelen, František - Vetterl, Vladimír
PY - 2001
TI - Electrochemical Detection of Interactions of Echinomycin with DNA at Mercury Film Electrodes (MFE).
PB - US-CZ Workshop on Electrochemical Sensors Prague
CY - Prague
SN - 8086238156
KW - DNA-echinomycin interaction
KW - electrochemical impedance spectroscopy;EIS
KW - DNA adsorption
KW - mercuiry film electrodes;
N2 - The dependence of the impedance Z and/or differential capacitance C of the electrode double layer on electrode potential E and on frequency in solutions of echinomycin with single stranded (ss) and double-helical (double stranded, ds) DNA was measured. Echinomycin gives a pseudocapacitance redox peak on the C-E curves at the potential of -0.53 V. This peak is observed with the dsDNA-echinomycin comlex as well, but not with ssDNA treated by echinomycin. The capacitance measurements can thus distinguish with the aid of bis-intercalator echinomycin the ss and ds form of DNA adsorbed at the electrode surface. This promise to use impedance measurements for detection of dsDNA in hybridization reactins.
ER -
HASOŇ, Stanislav, Jakub DVOŘÁK, František JELEN and Vladimír VETTERL. Electrochemical Detection of Interactions of Echinomycin with DNA at Mercury Film Electrodes (MFE). In \textit{Book of Abstracts, US-CZ Workshops on Electrochemical Sensors Prague 2001}. Prague: US-CZ Workshop on Electrochemical Sensors Prague, 2001, p.~42. ISBN~80-86238-15-6.
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