Unusual DNA binding properties of chelate ring-opening platinum complexes

HABTEMARIAM, Abraha, Kamila NEPLECHOVÁ, Viktor BRABEC, Nicola MARGIOTTA and Peter J. SADLER. Unusual DNA binding properties of chelate ring-opening platinum complexes. Journal of Inorganic Biochemistry. Lausanne: Elsevier, 1997, vol. 1997, No 67, p. 161. ISSN 0162-0134.

Basic information

• Original name: Unusual DNA binding properties of chelate ring-opening platinum complexes
• Authors: HABTEMARIAM, Abraha (826 United Kingdom of Great Britain and Northern Ireland), Kamila NEPLECHOVÁ (203 Czech Republic), Viktor BRABEC (203 Czech Republic, guarantor), Nicola MARGIOTTA (380 Italy) and Peter J. SADLER (826 United Kingdom of Great Britain and Northern Ireland).
• Edition: Journal of Inorganic Biochemistry, Lausanne, Elsevier, 1997, 0162-0134.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 10610 Biophysics
• Country of publisher: Switzerland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 1.342
• RIV identification code: RIV/00216224:14310/97:00007655
• Organization unit: Faculty of Science
• Keywords in English: chelate; platinum complexes; DNA binding
• Tags: chelate, DNA binding, platinum complexes

Abstract

Bis(aminophosphine) platinum complexes were studied from the point of view of their DNA binding. They were found to show a different binding manner from that of cisplatin.

Links

• GA203/95/1190, research and development project: Name: Struktura a vazba ve sloučeninách dusíku, fosforu, síry a selenu a v komplexech kovů triády železa s N,P,S-ligandy

Investor: Czech Science Foundation, Structure and Bonding in the Compounds of Nitrogen,Phosphorus,Sulfur and Selenium and in the Complexes of Fe,Co,and Ni with N,P,S-Ligands