VESELSKÁ, Renata, Petr KUGLÍK, Pavla HUBLAROVÁ, Hana ŠVÁCHOVÁ, Eva LŽIČAŘOVÁ, Jiřina RELICHOVÁ and Pavel CEJPEK. Nestin expression in cell lines derived from high-grade astrocytomas. In XI. Cytoskeletální klub. 2003.
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Basic information
Original name Nestin expression in cell lines derived from high-grade astrocytomas.
Authors VESELSKÁ, Renata (203 Czech Republic), Petr KUGLÍK (203 Czech Republic), Pavla HUBLAROVÁ (203 Czech Republic), Hana ŠVÁCHOVÁ (203 Czech Republic), Eva LŽIČAŘOVÁ (203 Czech Republic), Jiřina RELICHOVÁ (203 Czech Republic) and Pavel CEJPEK (203 Czech Republic, guarantor).
Edition XI. Cytoskeletální klub, 2003.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/03:00008674
Organization unit Faculty of Medicine
Keywords in English nestin; intermediate filaments; immunocytochemical and cytogenetic analysis; astrocytomas
Tags astrocytomas, immunocytochemical and cytogenetic analysis, intermediate filaments, nestin
Changed by Changed by: prof. RNDr. Renata Veselská, Ph.D., M.Sc., učo 1260. Changed: 6/4/2010 19:52.
Abstract
Two cell lines were established from biopsy samples of patients surgically treated for glioblastoma multiforme. Genetic abnormalities were studied on fresh bioptic material using interphase fluorescence in situ hybridization (iFISH); cultivated cell lines were analyzed by G-banding and spectral karyotyping (SKY). The expression of intermediate filament proteins (vimentin, GFAP, nestin) was analyzed at different passages for both cell lines.
Links
OC B19.001, research and development projectName: Genová diagnostika a terapie multiformního glioblastomu (Acronym: COST)
Investor: Ministry of Education, Youth and Sports of the CR, Gene Diagnostics and Therapy of Multiform Glioblastoma
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