VINKLEROVÁ, Jana and Alexandra ŠULCOVÁ. Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis. In Psychiatrie, Supplementum 1, 2003. Praha: Tigis, 2003, p. 54-54. ISBN 1212-6845.
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Basic information
Original name Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis
Authors VINKLEROVÁ, Jana (203 Czech Republic, guarantor) and Alexandra ŠULCOVÁ (203 Czech Republic).
Edition Praha, Psychiatrie, Supplementum 1, 2003, p. 54-54, 1 pp. 2003.
Publisher Tigis
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/03:00008723
Organization unit Faculty of Medicine
ISBN 1212-6845
Keywords in English cannabinoids; ACPA; JWH 015; leukocyte phagocytosis; chemiluminescence
Tags ACPA, cannabinoids, chemiluminescence, JWH 015, leukocyte phagocytosis
Changed by Changed by: MUDr. Jana Unar Vinklerová, Ph.D., MBA, učo 2545. Changed: 23/5/2003 10:05.
Abstract
The cannabinoids are involved in regulation of immune function. This action can be mediated either through cannabinoid receptors which subtypes CB1 and CB2 have been identified on leukocytes, or by non-receptor mechanism not clearly understood yet. The present study investigated th influence of the CB1 receptor agonist ACPA and the CB2 receptor agonist JWH 015 on the cellular immune function on leukocyte phagocytosis. Phagocytic activity of mouse leukocytes was measured in chemiluminescence (CL) assay using zymosan induction of phagocytosis and luminol potentiated of CL in vitro.
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