Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis

VINKLEROVÁ, Jana and Alexandra ŠULCOVÁ. Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis. In Psychiatrie, Supplementum 1, 2003. Praha: Tigis, 2003, p. 54-54. ISBN 1212-6845.

Basic information

Original name

Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis

Authors

VINKLEROVÁ, Jana (203 Czech Republic, guarantor) and Alexandra ŠULCOVÁ (203 Czech Republic)

Edition

Praha, Psychiatrie, Supplementum 1, 2003, p. 54-54, 1 pp. 2003

Publisher

Tigis

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Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/03:00008723

Organization unit

Faculty of Medicine

ISBN

1212-6845

Keywords in English

cannabinoids; ACPA; JWH 015; leukocyte phagocytosis; chemiluminescence

Tags

ACPA, cannabinoids, chemiluminescence, JWH 015, leukocyte phagocytosis

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Abstract

V originále

The cannabinoids are involved in regulation of immune function. This action can be mediated either through cannabinoid receptors which subtypes CB1 and CB2 have been identified on leukocytes, or by non-receptor mechanism not clearly understood yet. The present study investigated th influence of the CB1 receptor agonist ACPA and the CB2 receptor agonist JWH 015 on the cellular immune function on leukocyte phagocytosis. Phagocytic activity of mouse leukocytes was measured in chemiluminescence (CL) assay using zymosan induction of phagocytosis and luminol potentiated of CL in vitro.