IZAKOVIČOVÁ HOLLÁ, Lydie, Andrea STEJSKALOVÁ, Dana BUČKOVÁ, Marcel SCHÜLLER and Vladimír ZNOJIL. A gender-specific association between a novel A5495G variant in the endothelial nitrix oxide synthase gene (NOS3) and respiratory allergy in the Czech population. Eur.Respir.J. Leeds: Maney Publishing, 2003, vol. 22, Suppl 45, p. 581. ISSN 0904-1850.
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Basic information
Original name A gender-specific association between a novel A5495G variant in the endothelial nitrix oxide synthase gene (NOS3) and respiratory allergy in the Czech population
Authors IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor), Andrea STEJSKALOVÁ (203 Czech Republic), Dana BUČKOVÁ (203 Czech Republic), Marcel SCHÜLLER (203 Czech Republic) and Vladimír ZNOJIL (203 Czech Republic).
Edition Eur.Respir.J. Leeds, Maney Publishing, 2003, 0904-1850.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14330/03:00008574
Organization unit Faculty of Informatics
Keywords in English NOS; gene; polymorphism; gender; association
Tags association, gender, gene, NOS, polymorphism
Changed by Changed by: RNDr. JUDr. Vladimír Šmíd, CSc., učo 1084. Changed: 29/5/2004 17:17.
Abstract
Several studies suggest that abnormalities in nitrix oxide (NO) synthesis may contribute to the development of pulmonary diseases. We recently identified a novel variant within intron 4 of the NOS3 gene: A to G conversion at nucleotide position 5495. We have, therefore, performed a case-control study to investigate a plausible association between this polymorphism in the NOS3 gene and respiratory allergic diseases.
Links
GP310/03/P045, research and development projectName: Analýza polymorfizmů v genech pro syntetázu oxidu dusnatého (NOS) u atopického astmatu a jiných alergií v české populaci
Investor: Czech Science Foundation
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
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