The effects of cannabinoid CB1 receptor antagonist AM 251 on locomotor/exploratory behaviour and body weight in mice

ŠLAIS, Karel, Leoš LANDA and Alexandra ŠULCOVÁ. The effects of cannabinoid CB1 receptor antagonist AM 251 on locomotor/exploratory behaviour and body weight in mice. European Neuropsychopharmacology. Amsterdam: Elsevier, 2003, vol. 13, Suppl. 4, p. 417 - 417. ISSN 0924-977X.

Basic information

Original name

The effects of cannabinoid CB1 receptor antagonist AM 251 on locomotor/exploratory behaviour and body weight in mice

Authors

ŠLAIS, Karel (203 Czech Republic), Leoš LANDA (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic, guarantor)

Edition

European Neuropsychopharmacology, Amsterdam, Elsevier, 2003, 0924-977X

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.842

RIV identification code

RIV/00216224:14110/03:00008971

Organization unit

Faculty of Medicine

UT WoS

000185412300678

Keywords in English

body weight; AM 251; locomotor/exploratory behaviour; mice

Tags

AM 251, body weight, locomotor/exploratory behaviour, mice

Tags

International impact

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Abstract

V originále

The effects of the cannabinoid CB1 receptor antagonist AM 251 were assessed in adult, non-obese male mice. The changes in the behaviour recorded were aimed on locomotor/exploratory activity of mice in the open field test. The daily administration of AM 251 reduced dose-dependently and significantly body weight, while did not significantly affect locomotor/exploratpry activities neither after acute nor repeated administration.