MATULA, Petr, Magdalena SKALNÍKOVÁ, Michal KOZUBEK and Michael HAUSMANN. Improving measurement precision using automated micro-axial tomography. In Biophysics of the Genome. Brno: Masaryk University, 2003, p. 51-53. ISBN 80-210-3226-X.
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Basic information
Original name Improving measurement precision using automated micro-axial tomography
Authors MATULA, Petr (203 Czech Republic), Magdalena SKALNÍKOVÁ (203 Czech Republic), Michal KOZUBEK (203 Czech Republic, guarantor) and Michael HAUSMANN (276 Germany).
Edition Brno, Biophysics of the Genome, p. 51-53, 3 pp. 2003.
Publisher Masaryk University
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 20200 2.2 Electrical engineering, Electronic engineering, Information engineering
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14330/03:00009008
Organization unit Faculty of Informatics
ISBN 80-210-3226-X
Keywords in English human genome structure; image analysis
Tags human genome structure, Image analysis
Tags International impact
Changed by Changed by: prof. RNDr. Michal Kozubek, Ph.D., učo 3740. Changed: 29/10/2010 14:39.
Abstract
Distance measurement between small targets plays an important role in human genome research. The precision of such measurements depends on the quality of images, the localisation precision of the targets and the orientation of the line connecting the targets. In micro-axial tomography, the observed objects (cells) are fixed to a glass fibre, which can be rotated. By rotating the fibre the orientation of the measured targets can be changed. The relationship between the localisation precision and the orientation of the targets has been studied in simple simulations. In micro-axial tomography, two main approaches to measurement exist. Either one high-resolution image is reconstructed from the acquired tilted images and the measurements are performed on the single image or the images in the series are measured separately and the results are combined. Both approaches are compared and discussed here.
Links
IBS5004010, research and development projectName: Vývoj nových diagnostických technik pro onkologii
Investor: Academy of Sciences of the Czech Republic, Development of new diagnostic teniques for oncology
MSM 143300002, plan (intention)Name: Využití počítačové analýzy obrazu v optické mikroskopii
Investor: Ministry of Education, Youth and Sports of the CR, Application of computer image analysis in optical microscopy
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