Detailed Information on Publication Record
2003
Changes in Telomerase Activity, Expression and Splicing in Response to Differentiation of Normal and Carcinoma Colon Cells
FAJKUS, Jiří, Marek BORSKÝ, Zuzana KUNICKÁ, Martina KOVAŘÍKOVÁ, Dana DVOŘÁKOVÁ et. al.Basic information
Original name
Changes in Telomerase Activity, Expression and Splicing in Response to Differentiation of Normal and Carcinoma Colon Cells
Authors
FAJKUS, Jiří (203 Czech Republic, guarantor), Marek BORSKÝ (203 Czech Republic), Zuzana KUNICKÁ (203 Czech Republic), Martina KOVAŘÍKOVÁ (203 Czech Republic), Dana DVOŘÁKOVÁ (203 Czech Republic), Jiřina HOFMANOVÁ (203 Czech Republic) and Alois KOZUBÍK (203 Czech Republic)
Edition
Anticancer Research, Athens, INT INST ANTICANCER RESEARCH, 2003, 0250-7005
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Greece
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.347
RIV identification code
RIV/00216224:14310/03:00008576
Organization unit
Faculty of Science
UT WoS
000183471600064
Keywords in English
telomerase regulation; human colon cells; butyrate; alternative splicing; flow cytometry
Tags
International impact, Reviewed
Změněno: 30/6/2009 12:49, prof. RNDr. Jiří Fajkus, CSc.
Abstract
V originále
Downregulation of telomerase activity and expression occurs in response to butyrate-induced differentiation in normal and carcinoma colon cells. Differential splicing of hTERT mRNA may be involved in faster loss of telomerase activity in normal cells with respect to malignant cells.
Links
| IBS5004010, research and development project |
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| MSM 143100008, plan (intention) |
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