Mathematical model of peripheral blood stem cell harvest kinetics

MAYER, Jiří, Zdeněk POSPÍŠIL and Zdeněk KOŘÍSTEK. Mathematical model of peripheral blood stem cell harvest kinetics. Bone Marrow Transplantation. NPG, 2003, vol. 32, No 8, p. 749-757. ISSN 0268-3369.

Basic information

• Original name: Mathematical model of peripheral blood stem cell harvest kinetics
• Authors: MAYER, Jiří (203 Czech Republic, guarantor), Zdeněk POSPÍŠIL (203 Czech Republic) and Zdeněk KOŘÍSTEK (203 Czech Republic).
• Edition: Bone Marrow Transplantation, NPG, 2003, 0268-3369.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 2.172
• RIV identification code: RIV/00216224:14310/03:00009048
• Organization unit: Faculty of Science
• UT WoS: 000185799400002
• Keywords in English: mathematical model; cell separator; cell collection; peripheral blood stem cells; CD34+ cells; hematopoiesis
• Tags: CD34+ cells, cell collection, cell separator, hematopoiesis, mathematical model, peripheral blood stem cells

Abstract

A mathematical model of peripheral blood stem cell harvest was developped, taking two new parameters - number of recruited cells and efficiency of collection - into consideration in addition to concentration and collected ammount of cells. This model was tested on 241 harvest procedures in cancer patients, donors of allogenetic PBSC, and platelet donors, using different collection procedures, with Cobe Spectra Cell separator.

Links

• MSM 143100001, plan (intention): Name: Funkcionální diferenciální rovnice a matematicko-statistické modely

Investor: Ministry of Education, Youth and Sports of the CR, Functional-differential equations and mathematical-statistical models