J 2004

Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population

IZAKOVIČOVÁ HOLLÁ, Lydie, Michal JURAJDA, Antonín FASSMANN, Naděžda DVOŘÁKOVÁ, Vladimír ZNOJIL et. al.

Basic information

Original name

Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population

Name in Czech

Genetické varianty v promotoru genu pro matrix metaloproteinázu 1 (MMP-1) a riziko náchylnosti ke vzniku/a nebo závažnosti chronické parodontitidy v české populaci

Authors

IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor), Michal JURAJDA (203 Czech Republic), Antonín FASSMANN (203 Czech Republic), Naděžda DVOŘÁKOVÁ (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic)

Edition

J Clin Periodontol, Denmark, Munksgaard International Publishers Ltd. 2004, 0303-6979

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

Denmark

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.644

RIV identification code

RIV/00216224:14110/04:00009879

Organization unit

Faculty of Medicine

UT WoS

000222713500016

Keywords in English

periodontitis; MMP-1; matrix metalloproteinase; haplotype; gene

Tags

gene, haplotype, matrix metalloproteinase, MMP-1, periodontitis
Změněno: 17/6/2009 11:52, prof. MUDr. Lydie Izakovičová Hollá, Ph.D.

Abstract

ORIG CZ

V originále

Matrix metalloproteinase-1 (MMP-1) is a potent enzyme degrading extracellular matrix, which was implicated in the pathogenesis of chronic periodontitis. Therefore, the aim of our study was to examine the association between three promoter polymorphisms of the MMP-1 gene and chronic periodontitis susceptibility and/or severity in a Czech population.

In Czech

Matrix metaloproteináza 1 (MMP-1) je enzym degradující extracelulární matrix, který se účastní patogeneze chronické parodontitidy. Cílem naší práce bylo analyzovat asociaci mezi třemi promotorovými polymorfizmy v genu pro MMP-1 a náchylností ke vzniku chronické parodontitidy a/nebo její závažnosti v české populaci.

Links

MSM 141100002, plan (intention)
Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
Displayed: 11/11/2024 04:40