Genetic variations in the matrix metalloproteinase-1 (MMP-1)
promoter and risk of susceptibility and/or severity of chronic
periodontitis in the Czech population

J 2004

Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population

IZAKOVIČOVÁ HOLLÁ, Lydie, Michal JURAJDA, Antonín FASSMANN, Naděžda DVOŘÁKOVÁ, Vladimír ZNOJIL et. al.

Basic information

Original name

Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population

Name in Czech

Genetické varianty v promotoru genu pro matrix metaloproteinázu 1 (MMP-1) a riziko náchylnosti ke vzniku/a nebo závažnosti chronické parodontitidy v české populaci

Authors

IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor), Michal JURAJDA (203 Czech Republic), Antonín FASSMANN (203 Czech Republic), Naděžda DVOŘÁKOVÁ (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic)

Edition

J Clin Periodontol, Denmark, Munksgaard International Publishers Ltd. 2004, 0303-6979

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

Denmark

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.644

RIV identification code

RIV/00216224:14110/04:00009879

Organization unit

Faculty of Medicine

UT WoS

000222713500016

Keywords in English

periodontitis; MMP-1; matrix metalloproteinase; haplotype; gene

Abstract

ORIG CZ

V originále

Matrix metalloproteinase-1 (MMP-1) is a potent enzyme degrading extracellular matrix, which was implicated in the pathogenesis of chronic periodontitis. Therefore, the aim of our study was to examine the association between three promoter polymorphisms of the MMP-1 gene and chronic periodontitis susceptibility and/or severity in a Czech population.

In Czech

Matrix metaloproteináza 1 (MMP-1) je enzym degradující extracelulární matrix, který se účastní patogeneze chronické parodontitidy. Cílem naší práce bylo analyzovat asociaci mezi třemi promotorovými polymorfizmy v genu pro MMP-1 a náchylností ke vzniku chronické parodontitidy a/nebo její závažnosti v české populaci.

Links

MSM 141100002, plan (intention)

Name: Molekulární patofyziologie multigenních chorob

Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases

Citovat

IZAKOVIČOVÁ HOLLÁ, Lydie, Michal JURAJDA, Antonín FASSMANN, Naděžda DVOŘÁKOVÁ, Vladimír ZNOJIL and Jiří VÁCHA. Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population. J Clin Periodontol. Denmark: Munksgaard International Publishers Ltd., 2004, vol. 31, No 8, p. 685-690. ISSN 0303-6979.

@article{490261,
   author = {Izakovičová Hollá, Lydie and Jurajda, Michal and Fassmann, Antonín and Dvořáková, Naděžda and Znojil, Vladimír and Vácha, Jiří},
   article_location = {Denmark},
   article_number = {8},
   keywords = {periodontitis; MMP-1; matrix metalloproteinase; haplotype; gene},
   language = {eng},
   issn = {0303-6979},
   journal = {J Clin Periodontol},
   title = {Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population},
   volume = {31},
   year = {2004}
}

TY  - JOUR
ID  - 490261
AU  - Izakovičová Hollá, Lydie - Jurajda, Michal - Fassmann, Antonín - Dvořáková, Naděžda - Znojil, Vladimír - Vácha, Jiří
PY  - 2004
TI  - Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population
JF  - J Clin Periodontol
VL  - 31
IS  - 8
SP  - 685-690
EP  - 685-690
PB  - Munksgaard International Publishers Ltd.
SN  - 03036979
KW  - periodontitis
KW  - MMP-1
KW  - matrix metalloproteinase
KW  - haplotype
KW  - gene
N2  - Matrix metalloproteinase-1 (MMP-1) is a potent enzyme degrading extracellular matrix, which was implicated in the pathogenesis of chronic periodontitis. Therefore, the aim of our study was to examine the association between three promoter polymorphisms of the MMP-1 gene and chronic periodontitis susceptibility and/or severity in a Czech population.
ER  -

IZAKOVIČOVÁ HOLLÁ, Lydie, Michal JURAJDA, Antonín FASSMANN, Naděžda DVOŘÁKOVÁ, Vladimír ZNOJIL and Jiří VÁCHA. Genetic variations in the matrix metalloproteinase-1 (MMP-1) promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population. \textit{J Clin Periodontol}. Denmark: Munksgaard International Publishers Ltd., 2004, vol.~31, No~8, p.~685-690. ISSN~0303-6979.

Detailed Information on Publication Record