Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats

NOVÁKOVÁ, Jana. Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats. European Neuropsychopharmacology. Amsterdam (The Netherlands): Elsevier, 2003, vol. 13, Suppl. 4, p. S420-S420, 1 pp. ISSN 0924-977X.

Basic information

Original name

Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats

Authors

NOVÁKOVÁ, Jana (203 Czech Republic, guarantor)

Edition

European Neuropsychopharmacology, Amsterdam (The Netherlands), Elsevier, 2003, 0924-977X

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.842

RIV identification code

RIV/00216224:14110/03:00009234

Organization unit

Faculty of Medicine

Keywords in English

5-HT1 and 5-HT2 receptor ligands; methamphetamine; self-administration;rats

Tags

methamphetamine, rats, self-administration

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Abstract

V originále

Present work brings new aspects into the understanding of methamphetamine addiction studying the role of two different serotonergic receptor subtypes 5-HT1 and 5-HT2. According to our results, the most important inhibitory influence for the conditioned reward responding to methamphetamine i.v. self-administration showed pharmacological agonistic manipulation of the 5-HT1B receptor subtype.