DOSTÁLEK, Miroslav, Jiří SLÍVA, Eva HADAŠOVÁ and Josef TOMANDL. Combined treatment with methamphetamine and fluoxetine influences pharmacokinetic behaviour of dextromethorphane in the rat. Psychiatrie. Praha: Tigis s.r.o., 2003, vol. 7, suppl 1, p. 16-16. ISSN 1211-7579. |
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@article{490933, author = {Dostálek, Miroslav and Slíva, Jiří and Hadašová, Eva and Tomandl, Josef}, article_location = {Praha}, article_number = {suppl 1}, keywords = {methamphetamine; pharmacokinetics; dextromethorphan}, language = {eng}, issn = {1211-7579}, journal = {Psychiatrie}, title = {Combined treatment with methamphetamine and fluoxetine influences pharmacokinetic behaviour of dextromethorphane in the rat}, volume = {7}, year = {2003} }
TY - JOUR ID - 490933 AU - Dostálek, Miroslav - Slíva, Jiří - Hadašová, Eva - Tomandl, Josef PY - 2003 TI - Combined treatment with methamphetamine and fluoxetine influences pharmacokinetic behaviour of dextromethorphane in the rat JF - Psychiatrie VL - 7 IS - suppl 1 SP - 16-16 EP - 16-16 PB - Tigis s.r.o. SN - 12117579 KW - methamphetamine KW - pharmacokinetics KW - dextromethorphan N2 - The purpose of this study was to assess pharmacokinetics of dextromethorphane (model substrate of CYP2D2). The results suggest that fluoxetine therapy in methamphetamine dependece could slow down biodegradation of methamphetamine and this would enable to reduce methamphetamine doses without a decrease in psychotropic effect of drug. ER -
DOSTÁLEK, Miroslav, Jiří SLÍVA, Eva HADAŠOVÁ and Josef TOMANDL. Combined treatment with methamphetamine and fluoxetine influences pharmacokinetic behaviour of dextromethorphane in the rat. \textit{Psychiatrie}. Praha: Tigis s.r.o., 2003, vol.~7, suppl 1, p.~16-16. ISSN~1211-7579.
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