Detailed Information on Publication Record
2003
Frequency dependence of Ito and INa block in ventricular cardiomyocytes: comparison of the effect of ajmaline and propafenone
BÉBAROVÁ, Markéta, Peter MATEJOVIČ, Michal PÁSEK, Milena ŠIMURDOVÁ, Jiří ŠIMURDA et. al.Basic information
Original name
Frequency dependence of Ito and INa block in ventricular cardiomyocytes: comparison of the effect of ajmaline and propafenone
Authors
BÉBAROVÁ, Markéta (203 Czech Republic, guarantor, belonging to the institution), Peter MATEJOVIČ (703 Slovakia, belonging to the institution), Michal PÁSEK (203 Czech Republic, belonging to the institution), Milena ŠIMURDOVÁ (203 Czech Republic, belonging to the institution) and Jiří ŠIMURDA (203 Czech Republic, belonging to the institution)
Edition
Physiological Research, 2003
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30105 Physiology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/03:00009516
Organization unit
Faculty of Medicine
Keywords in English
frequency dependence; transient outward current; sodium current; antiarrhythmic drugs; ajmaline; propafenone; rat
Tags
Tags
International impact, Reviewed
Změněno: 19/1/2013 21:44, doc. MUDr. Markéta Bébarová, Ph.D.
Abstract
V originále
In contrast to propafenone, ajmaline induces frequency-independent block of INa and Ito. The difference is likely caused by variances in the values of rate constants related to the block of inactivated channels.
Links
| MSM 141100004, plan (intention) |
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