BÉBAROVÁ, Markéta, Peter MATEJOVIČ, Michal PÁSEK, Milena ŠIMURDOVÁ and Jiří ŠIMURDA. Comparison of ajmaline- and propafenone-induced block of Ito in rat ventricular myocytes. In Abstract Book of 3rd FEPS Congress. 2003.
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Basic information
Original name Comparison of ajmaline- and propafenone-induced block of Ito in rat ventricular myocytes
Authors BÉBAROVÁ, Markéta (203 Czech Republic, guarantor, belonging to the institution), Peter MATEJOVIČ (703 Slovakia, belonging to the institution), Michal PÁSEK (203 Czech Republic, belonging to the institution), Milena ŠIMURDOVÁ (203 Czech Republic, belonging to the institution) and Jiří ŠIMURDA (203 Czech Republic, belonging to the institution).
Edition Abstract Book of 3rd FEPS Congress, 2003.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30105 Physiology
Country of publisher France
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/03:00009521
Organization unit Faculty of Medicine
Keywords in English mathematical modelling; frequency dependence; transient outward current; rat; antiarrhythmic drugs; ajmaline; propafenone
Tags ajmaline, antiarrhythmic drugs, frequency dependence, mathematical modelling, propafenone, rat, transient outward current
Tags International impact
Changed by Changed by: doc. MUDr. Markéta Bébarová, Ph.D., učo 15000. Changed: 19/1/2013 21:45.
Abstract
The difference between ajmaline- and propafenone-induced block of Ito was analyzed both by experimental analysis and by mathematical modelling. The difference is caused by the variances in the values of rate constant related to block of inactivated channels.
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MSM 141100004, plan (intention)Name: Časná diagnostika kardiovaskulárních chorob
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