a 2003

Comparison of ajmaline- and propafenone-induced block of Ito in rat ventricular myocytes

BÉBAROVÁ, Markéta, Peter MATEJOVIČ, Michal PÁSEK, Milena ŠIMURDOVÁ, Jiří ŠIMURDA et. al.

Basic information

Original name

Comparison of ajmaline- and propafenone-induced block of Ito in rat ventricular myocytes

Authors

BÉBAROVÁ, Markéta (203 Czech Republic, guarantor, belonging to the institution), Peter MATEJOVIČ (703 Slovakia, belonging to the institution), Michal PÁSEK (203 Czech Republic, belonging to the institution), Milena ŠIMURDOVÁ (203 Czech Republic, belonging to the institution) and Jiří ŠIMURDA (203 Czech Republic, belonging to the institution)

Edition

Abstract Book of 3rd FEPS Congress, 2003

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30105 Physiology

Country of publisher

France

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/03:00009521

Organization unit

Faculty of Medicine

Keywords in English

mathematical modelling; frequency dependence; transient outward current; rat; antiarrhythmic drugs; ajmaline; propafenone

Tags

ajmaline, antiarrhythmic drugs, frequency dependence, mathematical modelling, propafenone, rat, transient outward current

Tags

International impact
Změněno: 19/1/2013 21:45, doc. MUDr. Markéta Bébarová, Ph.D.

Abstract

V originále

The difference between ajmaline- and propafenone-induced block of Ito was analyzed both by experimental analysis and by mathematical modelling. The difference is caused by the variances in the values of rate constant related to block of inactivated channels.

Links

MSM 141100004, plan (intention)
Name: Časná diagnostika kardiovaskulárních chorob
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