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@article{553813,
author = {Neradil, Jakub and Veselska, Renata and Slanina, Jiri},
article_location = {Praha},
article_number = {49},
keywords = {UVC; caffeic acid; UV-protective effect; alpha-tocopherol},
language = {eng},
issn = {0015-5500},
journal = {Folia Biologica},
title = {UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro},
volume = {2003},
year = {2003}
}
TY - JOUR
ID - 553813
AU - Neradil, Jakub - Veselska, Renata - Slanina, Jiri
PY - 2003
TI - UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro
JF - Folia Biologica
VL - 2003
IS - 49
SP - 197
EP - 197
PB - Akademie Ved Ceske Republiky
SN - 00155500
KW - UVC
KW - caffeic acid
KW - UV-protective effect
KW - alpha-tocopherol
N2 - Possible UVC-protective properties of caffeic acid (CA), a plant phenolic compound with antioxidant activity, were investigated on human KF1 diploid fibroblast and A431 epidermoid carcinoma cell lines. Cell populations, untreated and treated by antioxidants (CA and á-tocopherol), were irradiated by UVC at the wavelength of 254 nm and their proliferation activity was determined by the MTT-assay. Results show a strong protective effect of CA at both concentrations used (55.5 and 165.5 ěM). This protective ability is probably based on the antioxidant and scavenging activities of CA, which seems to be more efficient than á-tocopherol in protection against cytotoxic effect caused by UVC-irradiation.
ER -
NERADIL, Jakub, Renata VESELSKA a Jiri SLANINA. UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro. \textit{Folia Biologica}. Praha: Akademie Ved Ceske Republiky, roč.~2003, č.~49, s.~197-202. ISSN~0015-5500. 2003.
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