D 2004

Prognostic factors of the Pharynx and supraglottic Carcinoma

KOSTŘICA, Rom, Pavel SMILEK, Jan ROTTENBERG, Karel VESELÝ, Ladislav DUŠEK et. al.

Basic information

Original name

Prognostic factors of the Pharynx and supraglottic Carcinoma

Name (in English)

Prognostic factors of the Pharynx and supraglottic Carcinoma

Authors

KOSTŘICA, Rom (203 Czech Republic), Pavel SMILEK (203 Czech Republic, guarantor), Jan ROTTENBERG (203 Czech Republic), Karel VESELÝ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic) and Jiří HLOŽEK (203 Czech Republic)

Edition

Stuttgart, HNO Infromationen, p. 139-139, 2004

Publisher

Karl Demetr Verlag im Georg Thieme VErlag

Other information

Language

Czech

Type of outcome

Stať ve sborníku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Canada

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/04:00010082

Organization unit

Faculty of Medicine

ISBN

03 44-93 19

Keywords in English

Prognosis of head and neck carcinoma - DNA content - Ki-67
Změněno: 2/6/2004 08:02, doc. MUDr. Pavel Smilek, Ph.D.

Abstract

V originále

The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis treated at the Clinic of Otorhinolaryngology and Head and Neck Surgery in Brno within 1991 - 1999. Besides routine examinations, flow cytometric analysis of DNA was performed and Ki-67 marker was established by means of immunohistochemistry. The evaluation of kinetic parameters of the cellular cycle has revealed quite clearly the significantly lower share of SPF in tumors with poor prognosis. Tumors with direct progression immediately after treatment have shown statistically significantly higher share of cells in G2/M phase.

In English

The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis treated at the Clinic of Otorhinolaryngology and Head and Neck Surgery in Brno within 1991 - 1999. Besides routine examinations, flow cytometric analysis of DNA was performed and Ki-67 marker was established by means of immunohistochemistry. The evaluation of kinetic parameters of the cellular cycle has revealed quite clearly the significantly lower share of SPF in tumors with poor prognosis. Tumors with direct progression immediately after treatment have shown statistically significantly higher share of cells in G2/M phase.

Links

MSM 141100003, plan (intention)
Name: Zevní prostředí - karcinogeneze - onkologie
Investor: Ministry of Education, Youth and Sports of the CR, Environment - carcinogenesis - oncology