DAVID, Marek, Miroslav GABRIEL and Marie KOPECKÁ. Microtubules and Actin Structures in the Basidiomycetous Yeast, Cryptococcus laurentii. In Yeast Commission, Czechoslovak Society for Microbiology. 32nd ANNUAL CONFERENCE ON YEASTS. Smolenice: Yeast Commission, Czechoslovak Society for Microbiology, 2004, p. 39-39, 2 pp. ISSN 1336-4839.
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Basic information
Original name Microtubules and Actin Structures in the Basidiomycetous Yeast, Cryptococcus laurentii
Name in Czech Mikrotubuly a aktinové struktury u basidiomycetové kvasinky, Cryptococcus laurentii
Authors DAVID, Marek (203 Czech Republic, belonging to the institution), Miroslav GABRIEL (203 Czech Republic, guarantor, belonging to the institution) and Marie KOPECKÁ (203 Czech Republic, belonging to the institution).
Edition Smolenice, 32nd ANNUAL CONFERENCE ON YEASTS, p. 39-39, 2 pp. 2004.
Publisher Yeast Commission, Czechoslovak Society for Microbiology
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW abstrakt
RIV identification code RIV/00216224:14110/04:00011439
Organization unit Faculty of Medicine
ISSN 1336-4839
Keywords in English Cryptococcus laurentii; cytoskeleton; basidiomycetous yeast
Tags basidiomycetous yeast, Cryptococcus laurentii, Cytoskeleton
Changed by Changed by: prof. MUDr. Marie Kopecká, CSc., učo 2342. Changed: 9/3/2011 09:24.
Abstract
Cytoskeleton was investigated by immunofluorescence in potentially pathogenic basidiomycetous yeast Cryptococcus laurentii. Cytoplasmic microtubules formed a random network and invaded into growing sterigma and bud.Before mitosis, nucleus migrated to the bud, while cytoplasmic microtubules dissapeared. During mitosis nuclear division occurred. One of the novel nuclei remained in the daughter cell, while the other moved back to the mother. After the mitosis, the mitotic spindle disassembled, while cytoplazmic microtubules re-appeared. From the actin structures we detected only F-actin patches in the growing and mature bud. Actin cables and actin ring were not seen yet. Even though the yeast was considered non-pathogenic for man for long time, recently reports about its opportunistic pathogeny especially in immunosuppressive patients appeared. Therefore it is important to obtain more information about this yeast on cellular and molecular level. This work was supported by grant GAČR 310/03/1195 (M.G.).
Links
GA310/03/1195, research and development projectName: Cytoskelet jako terčová struktura pro studium účinku antifungálních látek u patogenních kvasinek
Investor: Czech Science Foundation
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