Detailed Information on Publication Record
1991
Low content of mitochondrial ATPase in brown adipose tissue is the result of post-transcriptional regulation
HOUŠTĚK, Josef, Petr TVRDÍK, Stanislav PAVELKA and Marie BAUDYŠOVÁBasic information
Original name
Low content of mitochondrial ATPase in brown adipose tissue is the result of post-transcriptional regulation
Authors
HOUŠTĚK, Josef, Petr TVRDÍK, Stanislav PAVELKA and Marie BAUDYŠOVÁ
Edition
FEBS Letters [IF=3.479 (1990); SCI #cit.<22>], 1991, 0014-5793
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Netherlands
Confidentiality degree
není předmětem státního či obchodního tajemství
Organization unit
Faculty of Science
Keywords in English
ATPase; brown adipose tissue; cytochrome oxidase; mitochondrion; nuclear gene; transcription
Tags
International impact, Reviewed
Změněno: 4/1/2009 07:59, doc. RNDr. Stanislav Pavelka, CSc.
Abstract
V originále
The mRNA levels of ATPase beta, ATPase 6, cytochrome oxidase (COX) VIb and COX I subunits were found to be 2.4-13.8-fold higher in brown adipose tissue (BAT) than in heart, skeletal muscle, brain and liver of mice. The comparison with tissue contents of ATPase and COX revealed that the selective, 5-11-fold reduction of ATPase in BAT is not caused by decreased transcription of ATPase genes. The results indicate that the biosynthesis of mitochondrial ATPase in BAT is post-transcriptionally regulated.
Links
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