ESFANDIARI, Ali, Claire GAGELIN, Jean-Michel GAVARET, Stanislav PAVELKA, Ana-Maria LENNON, Michel PIERRE and Francoise COURTIN. Induction of type III-deiodinase activity in astroglial cells by retinoids. Glia [IF=5.096 (1993); SCI #cit.<35>]. 1994, vol. 11, 6,, p. 255-261. ISSN 0894-1491. |
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@article{555629, author = {Esfandiari, Ali and Gagelin, Claire and Gavaret, JeanandMichel and Pavelka, Stanislav and Lennon, AnaandMaria and Pierre, Michel and Courtin, Francoise}, article_number = {6,}, keywords = {Brain; cultured astrocytes; deiodinase; retinoic acid; thyroid hormones}, language = {eng}, issn = {0894-1491}, journal = {Glia [IF=5.096 (1993); SCI #cit.<35>]}, title = {Induction of type III-deiodinase activity in astroglial cells by retinoids}, volume = {11}, year = {1994} }
TY - JOUR ID - 555629 AU - Esfandiari, Ali - Gagelin, Claire - Gavaret, Jean-Michel - Pavelka, Stanislav - Lennon, Ana-Maria - Pierre, Michel - Courtin, Francoise PY - 1994 TI - Induction of type III-deiodinase activity in astroglial cells by retinoids JF - Glia [IF=5.096 (1993); SCI #cit.<35>] VL - 11 IS - 6, SP - 255-261 EP - 255-261 SN - 08941491 KW - Brain KW - cultured astrocytes KW - deiodinase KW - retinoic acid KW - thyroid hormones N2 - Thyroid hormones and retinoic acid (RA) are important modulators of growth, development, and differentiation. The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-RA caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. All-trans-RA (5 uM) had little or no effect on type II deiodinase, the enzyme which catalyzes the activation of thyroxine to 3,5,3'-triiodothyronine. ER -
ESFANDIARI, Ali, Claire GAGELIN, Jean-Michel GAVARET, Stanislav PAVELKA, Ana-Maria LENNON, Michel PIERRE and Francoise COURTIN. Induction of type III-deiodinase activity in astroglial cells by retinoids. \textit{Glia [IF=5.096 (1993); SCI \#{}cit.$<$35$>$]}. 1994, vol.~11, 6,, p.~255-261. ISSN~0894-1491.
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