ŠEDO, Ondrej, Sabina BILLOVÁ, Eladia Maria PENA MÉNDEZ, Emil PALEČEK and Josef HAVEL. Derivatisation of peptides with osmium tetroxide, 2,2-bipyridine: capillary electrophoretic and MALDITOF mass spectrometric study. Analytica Chimica Acta. Amsterdam: Elsevier Science Publishers, 2004, vol. 515, No 2, p. 261-269. ISSN 0003-2670.
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Basic information
Original name Derivatisation of peptides with osmium tetroxide, 2,2-bipyridine: capillary electrophoretic and MALDITOF mass spectrometric study
Name in Czech Derivatizace peptidů činidlem oxid osmičelý-bipyridin: kapilárně elektroforetická a MALDI-TOF hmotnostně spektrometrická studie
Authors ŠEDO, Ondrej (203 Czech Republic), Sabina BILLOVÁ (203 Czech Republic), Eladia Maria PENA MÉNDEZ (724 Spain), Emil PALEČEK (203 Czech Republic) and Josef HAVEL (203 Czech Republic, guarantor).
Edition Analytica Chimica Acta, Amsterdam, Elsevier Science Publishers, 2004, 0003-2670.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10406 Analytical chemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.588
RIV identification code RIV/00216224:14310/04:00011499
Organization unit Faculty of Science
UT WoS 000222370100003
Keywords in English Peptide derivatisation; Osmium tetroxide; Bipyridine; CZE; MALDI-TOF MS; PSD
Tags bipyridine, CZE, MALDI-TOF MS, osmium tetroxide, Peptide derivatisation, PSD
Changed by Changed by: Mgr. Ondrej Šedo, Ph.D., učo 13589. Changed: 14/2/2005 14:24.
Abstract
Site-specific chemical modification is a useful technology in characterisation of proteins, but the number of chemical probes of the protein structure reacting with proteins under mild conditions in aqueous solutions is rather limited. Here we studied the reaction of osmium tetroxide, 2,2-bipyridine (Os,bipy) with several peptides using capillary zone electrophoresis (CZE) and matrix-assisted laser desorption-ionisationCtime-of-flight mass spectrometry (MALDICTOF MS).
Abstract (in Czech)
V práci byla studována derivatizace peptidů činidlem oxid osmičelý-bipyridin metodami kapilární zónové elektroforézy a hmotnostní spektrometrie MALDI-TOF.
Links
GA305/03/1100, research and development projectName: Syntéza a studium neuroprotektivních peptidů odvozených od humaninu
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