LANDA, Leoš, Karel ŠLAIS, Alexandra ŠULCOVÁ and Mariana HANESOVÁ. Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice. Psychiatrie. Praha: Tigis, 2004, vol. 8, Suppl. 4, p. 31-31. ISSN 1211-7579.
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Basic information
Original name Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice
Name (in English) Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice
Authors LANDA, Leoš (203 Czech Republic, guarantor), Karel ŠLAIS (203 Czech Republic), Alexandra ŠULCOVÁ (203 Czech Republic) and Mariana HANESOVÁ (703 Slovakia).
Edition Psychiatrie, Praha, Tigis, 2004, 1211-7579.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/04:00010276
Organization unit Faculty of Medicine
Keywords in English behavioural sensitization; methamphetamine; memantine; open field test; mice
Tags behavioural sensitization, Memantine, methamphetamine, mice, open field test
Changed by Changed by: doc. Mgr. MVDr. Leoš Landa, Ph.D., učo 70449. Changed: 13/9/2004 13:01.
Abstract
Methamphetamine (MET) similarly to other psychostimulant drugs invokes during its repeated administration a significant increase in behavioural responses. This phenomenon is termed behavioural sensitization. There are various reports on involvement of N-methyl-D-aspartate (NMDA) receptor activity in the development and expression of behavioural sensitization, although results of them are rather controversial. Thus, the present study was designed to investigate a possible influence of NMDA receptor non-competitive antagonist memantine (MEM) on sensitization to methamphetamine effects on mouse locomotor/exploratory behaviour in the open field test.
Abstract (in English)
Methamphetamine (MET) similarly to other psychostimulant drugs invokes during its repeated administration a significant increase in behavioural responses. This phenomenon is termed behavioural sensitization. There are various reports on involvement of N-methyl-D-aspartate (NMDA) receptor activity in the development and expression of behavioural sensitization, although results of them are rather controversial. Thus, the present study was designed to investigate a possible influence of NMDA receptor non-competitive antagonist memantine (MEM) on sensitization to methamphetamine effects on mouse locomotor/exploratory behaviour in the open field test.
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