Detailed Information on Publication Record
2004
Impact of phenotyping CYP2D6 in psychiatry
ŽOURKOVÁ, Alexandra, Eva HADAŠOVÁ, Lucie PILAŘOVÁ, Miroslav ROBEŠ, Barbora RAVČUKOVÁ et. al.Basic information
Original name
Impact of phenotyping CYP2D6 in psychiatry
Name in Czech
Vliv fenotypizace CYP2D6 v psychiatrii
Authors
ŽOURKOVÁ, Alexandra (203 Czech Republic, guarantor), Eva HADAŠOVÁ (203 Czech Republic), Lucie PILAŘOVÁ (203 Czech Republic), Miroslav ROBEŠ (203 Czech Republic), Barbora RAVČUKOVÁ (203 Czech Republic) and Tomáš KAŠPÁREK (203 Czech Republic)
Edition
Psychiatrie, Praha, TIGIS s.r.o. 2004, 1211-7579
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/04:00010287
Organization unit
Faculty of Medicine
Keywords in English
phenotype; genotype; CYP2D6; clinical outcome
Tags
Tags
International impact
Změněno: 25/11/2006 10:12, prof. MUDr. Alexandra Žourková, CSc.
V originále
The paper deal with comparison of distribution therapeutic efficacy and side effects of long term paroxetine treatment within 50 patients genotyped and phenotyped to determine their metabolic status. No variation in therapeutic efficacy and common adverse effects between subjects classified as poor metabilisers and extensice metabolisers were found. A significantkly higher rate of sexual dysfunction was recored among patients with a PM Phenotype.
In Czech
Článek uvádí rozložení metabolického statusu u pacientů léčených paroxetinem. Srovnává vedl.účinky léčby a pomalý metabolický fenotyp. Rozdíl byl nalezen ve výskytu sex.dysfunkcí, který byl vyšší u pomalého fenotypu.