| SKŘIČKOVÁ, Jana a Lenka BABIČKOVÁ. Influencing the epidermal growth factor receptor - new prospects in the treatment of non-small-cell bronchogenic carcinoma. Studia Pneumologica et Phthiseologica. Praha: TRIOS, spol. s r.o., Praha, 2004, roč. 64, č. 3, s. 111-116. ISSN 1213-810X. |
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@article{557979,
author = {Skřičková, Jana and Babičková, Lenka},
article_location = {Praha},
article_number = {3},
keywords = {non-small-cell bronchogenic carcinomua; oncological therpy; epidermal growth factor receptor (EGFR); EGFR tyrosinekinase inhibitors; gefitinib},
language = {eng},
issn = {1213-810X},
journal = {Studia Pneumologica et Phthiseologica},
title = {Influencing the epidermal growth factor receptor - new prospects in the treatment of non-small-cell bronchogenic carcinoma},
volume = {64},
year = {2004}
}
TY - JOUR
ID - 557979
AU - Skřičková, Jana - Babičková, Lenka
PY - 2004
TI - Influencing the epidermal growth factor receptor - new prospects in the treatment of non-small-cell bronchogenic carcinoma
JF - Studia Pneumologica et Phthiseologica
VL - 64
IS - 3
SP - 111-116
EP - 111-116
PB - TRIOS, spol. s r.o., Praha
SN - 1213810X
KW - non-small-cell bronchogenic carcinomua
KW - oncological therpy
KW - epidermal growth factor receptor (EGFR)
KW - EGFR tyrosinekinase inhibitors
KW - gefitinib
N2 - To influence natural regulatory mechnisms, which control the metabolism, proliferation and migration of tumour cells, biological therapy resorts to low-molecular preparations, macromolecules and cellular immune-type effectors. Today we have primarily information on the influencing of the epidemal growth factor receptor - EGFR.Research concentrates above all on the possibility of inhibiting the intracellular domains of the EGF receptor that has a tyrosinekinase activity. This oncological tratment targes intracellular mechanism of the transfer ot the signal taht calls forth changes in the proliferation activity of tunour cells. In their paper the authors discuss various possibilities of influencing EGFR and their appliction in clinical practice.
ER -
SKŘIČKOVÁ, Jana a Lenka BABIČKOVÁ. Influencing the epidermal growth factor receptor - new prospects in the treatment of non-small-cell bronchogenic carcinoma. \textit{Studia Pneumologica et Phthiseologica}. Praha: TRIOS, spol. s r.o., Praha, 2004, roč.~64, č.~3, s.~111-116. ISSN~1213-810X.
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