Genetic variations in the human gelatinase A (MMP-2) promoter
are not associated with susceptibility to, and severity of,
chronic periodontitis

J 2005

Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis

IZAKOVIČOVÁ HOLLÁ, Lydie, Antonín FASSMANN, Anna VAŠKŮ, Monika PÁVKOVÁ GOLDBERGOVÁ, Michal BERÁNEK et. al.

Basic information

Original name

Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis

Name in Czech

Genetické varianty v promotoru genu pro lidskou gelatinázu (MMP-2) nejsou asociovány s náchylností ke vzniku chronické parodontitidy ani její závažností

Authors

IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor), Antonín FASSMANN (203 Czech Republic), Anna VAŠKŮ (203 Czech Republic), Monika PÁVKOVÁ GOLDBERGOVÁ (203 Czech Republic), Michal BERÁNEK (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic), Jiří VANĚK (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic)

Edition

J Periodontol, Chicago, American Academy of Periodontology, 2005, 0022-3492

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.784

RIV identification code

RIV/00216224:14110/05:00013560

Organization unit

Faculty of Medicine

UT WoS

000230774200002

Keywords in English

gelatinase A; MMP-2; gene; polymorphism; haplotype; periodontitis

Abstract

ORIG CZ

V originále

Gelatinase A (matrix metalloproteinase-2, MMP-2) has been shown to play an important role in the pathogenesis of several disorders, including periodontal diseases. In this study, we test the hypothesis that variations in this gene influence the development and severity of chronic periodontitis.

In Czech

Gelatináza A (matrix metaloproteináza 2, MMP-2) hraje důležitou úlohu v patogeneze některých nemocí, včetně onemocnění parodontu. V této práci jsme testovali hypotézu, že varianty v tomto genu ovlivňují rozvoj a závažnost chronické parodontitidy.

Links

MSM 141100002, plan (intention)

Name: Molekulární patofyziologie multigenních chorob

Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases

Citovat

IZAKOVIČOVÁ HOLLÁ, Lydie, Antonín FASSMANN, Anna VAŠKŮ, Monika PÁVKOVÁ GOLDBERGOVÁ, Michal BERÁNEK, Vladimír ZNOJIL, Jiří VANĚK and Jiří VÁCHA. Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis. J Periodontol. Chicago: American Academy of Periodontology, 2005, vol. 76, No 7, p. 15-19. ISSN 0022-3492.

@article{561458,
   author = {Izakovičová Hollá, Lydie and Fassmann, Antonín and Vašků, Anna and Pávková Goldbergová, Monika and Beránek, Michal and Znojil, Vladimír and Vaněk, Jiří and Vácha, Jiří},
   article_location = {Chicago},
   article_number = {7},
   keywords = {gelatinase A; MMP-2; gene; polymorphism; haplotype; periodontitis},
   language = {eng},
   issn = {0022-3492},
   journal = {J Periodontol},
   title = {Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis},
   volume = {76},
   year = {2005}
}

TY  - JOUR
ID  - 561458
AU  - Izakovičová Hollá, Lydie - Fassmann, Antonín - Vašků, Anna - Pávková Goldbergová, Monika - Beránek, Michal - Znojil, Vladimír - Vaněk, Jiří - Vácha, Jiří
PY  - 2005
TI  - Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis
JF  - J Periodontol
VL  - 76
IS  - 7
SP  - 15-19
EP  - 15-19
PB  - American Academy of Periodontology
SN  - 00223492
KW  - gelatinase A
KW  - MMP-2
KW  - gene
KW  - polymorphism
KW  - haplotype
KW  - periodontitis
N2  - Gelatinase A (matrix metalloproteinase-2, MMP-2) has been shown to play an important role in the pathogenesis of several disorders, including periodontal diseases. In this study, we test the hypothesis that variations in this gene influence the development and severity of chronic periodontitis.
ER  -

IZAKOVIČOVÁ HOLLÁ, Lydie, Antonín FASSMANN, Anna VAŠKŮ, Monika PÁVKOVÁ GOLDBERGOVÁ, Michal BERÁNEK, Vladimír ZNOJIL, Jiří VANĚK and Jiří VÁCHA. Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis. \textit{J Periodontol}. Chicago: American Academy of Periodontology, 2005, vol.~76, No~7, p.~15-19. ISSN~0022-3492.

Detailed Information on Publication Record