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@proceedings{564259, author = {Bébarová, Markéta and Matejovič, Peter and Pásek, Michal and Šimurdová, Milena and Šimurda, Jiří}, booktitle = {Proceeding of Workshop in Cardiovascular Physiology: Signal transduction in Cardio-Vascular System}, keywords = {ionic currents; rate dependence; action potential; rat}, language = {eng}, title = {Membrane currents underlying rate-dependent changes of action potential in rat ventricular myocytes}, year = {2004} }
TY - CONF ID - 564259 AU - Bébarová, Markéta - Matejovič, Peter - Pásek, Michal - Šimurdová, Milena - Šimurda, Jiří PY - 2004 TI - Membrane currents underlying rate-dependent changes of action potential in rat ventricular myocytes KW - ionic currents KW - rate dependence KW - action potential KW - rat N2 - The rate-dependent modulation of action potential (AP) playes an important role in the regulation of the excitation-contraction coupling and in the protective antiarrhythmic mechanisms in cardiac cells. We can conclude that the main determinants of rate-dependent variations of AP duration in rat ventricular myocytes are the calcium current ICa and the transient outward current Ito. Under our experimental conditions, participation of other current components was negligible. ER -
BÉBAROVÁ, Markéta, Peter MATEJOVIČ, Michal PÁSEK, Milena ŠIMURDOVÁ and Jiří ŠIMURDA. Membrane currents underlying rate-dependent changes of action potential in rat ventricular myocytes. In \textit{Proceeding of Workshop in Cardiovascular Physiology: Signal transduction in Cardio-Vascular System}. 2004.
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