ČEŠKOVÁ, Eva, Tomáš NOVOTNÝ, A. FLORIÁNOVÁ, Vítězslav PÁLENSKÝ, Radovan PŘIKRYL and J. TOMANOVÁ. Safety and tolerability of second and third generation antipsychotic (Safety and tolerability of second and third gneration antipsychotic). Psychiatrie, časopis pro moderní psychiatrii. Praha: Tigis, 2004, vol. 8, Suppl.4, p. 16. ISSN 1211-7579. |
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@article{564458, author = {Češková, Eva and Novotný, Tomáš and Floriánová, A. and Pálenský, Vítězslav and Přikryl, Radovan and Tomanová, J.}, article_location = {Praha}, article_number = {Suppl.4}, keywords = {safety and tolerability; antipsychotics; QT interval}, language = {cze}, issn = {1211-7579}, journal = {Psychiatrie, časopis pro moderní psychiatrii}, title = {Safety and tolerability of second and third generation antipsychotic}, volume = {8}, year = {2004} }
TY - JOUR ID - 564458 AU - Češková, Eva - Novotný, Tomáš - Floriánová, A. - Pálenský, Vítězslav - Přikryl, Radovan - Tomanová, J. PY - 2004 TI - Safety and tolerability of second and third generation antipsychotic JF - Psychiatrie, časopis pro moderní psychiatrii VL - 8 IS - Suppl.4 SP - 16 EP - 16 PB - Tigis SN - 12117579 KW - safety and tolerability KW - antipsychotics KW - QT interval N2 - Prolongation of the QT interval is of concern since the pacients may be at risk for TdP, a serious ventricular arrythmia.In hospitalised psychiatric patients a 12-lead ECG was recorded, the QT interval was measured manually, the Bazett formula was used for correction. The total number of 375 ECG records was obtained. In 11 of 375 records(i.e.2,9%) the borderline or pathologics valuesof QT interval were found. The occurrence of abnormal QTc was lower than in so-far avilable literature. This could be connected with the change of spectrum of antipsychotics used, the general trend to lower doses of antipsychotics. ER -
ČEŠKOVÁ, Eva, Tomáš NOVOTNÝ, A. FLORIÁNOVÁ, Vítězslav PÁLENSKÝ, Radovan PŘIKRYL and J. TOMANOVÁ. Safety and tolerability of second and third generation antipsychotic (Safety and tolerability of second and third gneration antipsychotic). \textit{Psychiatrie, časopis pro moderní psychiatrii}. Praha: Tigis, 2004, vol.~8, Suppl.4, p.~16. ISSN~1211-7579.
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