LANGHAM, Elise, Rychard CLAYTON, Michal PÁSEK and Clive ORCHARD. A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes. In Meeting of The Physiological Society (Oxford). 2004.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes
Name in Czech Výpočtový model účinku acidózy na intracelulární Ca2+ u komorové buňky potkana
Authors LANGHAM, Elise (826 United Kingdom of Great Britain and Northern Ireland), Rychard CLAYTON (826 United Kingdom of Great Britain and Northern Ireland), Michal PÁSEK (203 Czech Republic, guarantor) and Clive ORCHARD (826 United Kingdom of Great Britain and Northern Ireland).
Edition Meeting of The Physiological Society (Oxford), 2004.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10610 Biophysics
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/04:00030848
Organization unit Faculty of Medicine
Keywords in English cardiac cell; acidosis; quantitative modelling
Tags acidosis, Cardiac cell, Quantitative modelling
Tags International impact, Reviewed
Changed by Changed by: doc. Ing. Michal Pásek, Ph.D., učo 46541. Changed: 2/1/2010 11:02.
Abstract
The model of rat ventricular myocyte was used to investigate the physiological consequences of acidosis. The results of simulations were in agreement with experimental observations and showed that acidosis causes increase of intracellular Na+, intracellular Ca2+ and amplitude of Cai transients.
Abstract (in Czech)
Práce prezentuje využití matematického modelu ventrikulární buňky potkana k analýze účinků acidózy na elektrofyziologické vlastnosti srdečních buněk a intracelulární iontovou rovnováhu.
PrintDisplayed: 26/7/2024 03:24