J 2004

Genome differences and detection of pathogenic Treponema pallidum subspecies

MATĚJKOVÁ, Petra, David ŠMAJS, S.J. NORRIS and G.M. WEINSTOCK

Basic information

Original name

Genome differences and detection of pathogenic Treponema pallidum subspecies

Name in Czech

Rozdíly v genomech patogenních poddruhů Treponema pallidum

Authors

MATĚJKOVÁ, Petra (203 Czech Republic), David ŠMAJS (203 Czech Republic, guarantor), S.J. NORRIS (840 United States of America) and G.M. WEINSTOCK (724 Spain)

Edition

Clin. Microbiol. Infec. 2004, 1198-743X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.361

RIV identification code

RIV/00216224:14110/04:00011950

Organization unit

Faculty of Medicine

Keywords in English

comparative genomics; Treponema pallidum
Změněno: 30/5/2005 13:11, prof. MUDr. David Šmajs, Ph.D.

Abstract

V originále

No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts).

In Czech

Byly zjišťovány rozdíly v genomech patogenních poddruhů Treponema pallidum. Genomy Treponema pallidum ssp. pallidum a pertenue se liší jedním nukleotidem na 1640 párů bází (celkem asi 700 nts párů bází ).

Links

GA310/04/0021, research and development project
Name: Postgenomické studie syfilitické spirochety Treponema pallidum
Investor: Czech Science Foundation, Postgenomic studies on Treponema pallidum, the syphilis spirochete
NI7351, research and development project
Name: Komparativní genomika patogenních spirochet rodu Treponema: cesta k sekvenčně specifické diagnostice
Investor: Ministry of Health of the CR