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@article{565518,
author = {Bakonyi, Tamás and Hubálek, Zdeněk and Rudolf, Ivo and Nowotny, Norbert},
article_location = {Atlanta},
article_number = {2},
keywords = {Rabensburg; south Moravia; mosquito-borne virus; West Nile virus; sequencing; complete genome},
issn = {1080-6040},
journal = {Emerging Infectious Diseases},
title = {Novel flavivirus or new lineage of West Nile virus, Central Europe},
url = {http://www.cdc.gov/ncidod/EID/vol11no02/04-1028.htm},
volume = {11},
year = {2005}
}
TY - JOUR
ID - 565518
AU - Bakonyi, Tamás - Hubálek, Zdeněk - Rudolf, Ivo - Nowotny, Norbert
PY - 2005
TI - Novel flavivirus or new lineage of West Nile virus, Central Europe
JF - Emerging Infectious Diseases
VL - 11
IS - 2
SP - 225-231
EP - 225-231
PB - CDC
SN - 10806040
KW - Rabensburg
KW - south Moravia
KW - mosquito-borne virus
KW - West Nile virus
KW - sequencing
KW - complete genome
UR - http://www.cdc.gov/ncidod/EID/vol11no02/04-1028.htm
N2 - A flavivirus (strain 97-103) was isolated from Culex pipens mosquitoes in 1997 following floods in South Moravia, Czech Republic. The strain exhibited close antigenic relationship to West Nile virus (WNV) prototype strain Eg-101 in a cross-neutralization test. In this study, mouse pathogenicity characteristics and the complete nucleotide and putative amino acid sequences of isolate 97-103, named Rabensburg virus (RabV) after a nearby Austrian city, were determined. RabV shares only 75%-77% nucleotide identity and 89%-90% amino acid identity with representative strains of WNV lineages 1 and 2. Another RabV strain (99-222) was isolated in the same location two years later; it showed >99% nucleotide identity to strain 97-103. Phylogenetic analyses of RabV, WNV strains, and other members of the Japanese encephalitis virus (JEV) complex clearly demonstrated that RabV is either a new (third) lineage of WNV or a novel flavivirus of the JEV group.
ER -
BAKONYI, Tamás, Zdeněk HUBÁLEK, Ivo RUDOLF and Norbert NOWOTNY. Novel flavivirus or new lineage of West Nile virus, Central Europe. \textit{Emerging Infectious Diseases}. Atlanta: CDC, 2005, vol.~11, No~2, p.~225-231. ISSN~1080-6040.
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