Detailed Information on Publication Record
2005
Novel flavivirus or new lineage of West Nile virus, Central Europe
BAKONYI, Tamás, Zdeněk HUBÁLEK, Ivo RUDOLF and Norbert NOWOTNYBasic information
Original name
Novel flavivirus or new lineage of West Nile virus, Central Europe
Name in Czech
Nový flavivirus nebo nová genomická linie viru West Nile ve střední Evropě
Authors
BAKONYI, Tamás, Zdeněk HUBÁLEK, Ivo RUDOLF and Norbert NOWOTNY
Edition
Emerging Infectious Diseases, Atlanta, CDC, 2005, 1080-6040
Other information
Type of outcome
Článek v odborném periodiku
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 5.308
Organization unit
Faculty of Science
UT WoS
000226856900005
Keywords in English
Rabensburg; south Moravia; mosquito-borne virus; West Nile virus; sequencing; complete genome
Změněno: 9/3/2005 10:02, prof. RNDr. Zdeněk Hubálek, DrSc.
Abstract
V originále
A flavivirus (strain 97-103) was isolated from Culex pipens mosquitoes in 1997 following floods in South Moravia, Czech Republic. The strain exhibited close antigenic relationship to West Nile virus (WNV) prototype strain Eg-101 in a cross-neutralization test. In this study, mouse pathogenicity characteristics and the complete nucleotide and putative amino acid sequences of isolate 97-103, named Rabensburg virus (RabV) after a nearby Austrian city, were determined. RabV shares only 75%-77% nucleotide identity and 89%-90% amino acid identity with representative strains of WNV lineages 1 and 2. Another RabV strain (99-222) was isolated in the same location two years later; it showed >99% nucleotide identity to strain 97-103. Phylogenetic analyses of RabV, WNV strains, and other members of the Japanese encephalitis virus (JEV) complex clearly demonstrated that RabV is either a new (third) lineage of WNV or a novel flavivirus of the JEV group.
Links
GA206/03/0726, research and development project |
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