J 2004

Prolaction levels in risperidone treatment of first - episode schizophrenia

ČEŠKOVÁ, Eva, Radovan PŘIKRYL, Tomáš KAŠPÁREK and Marta ONDRUŠOVÁ

Basic information

Original name

Prolaction levels in risperidone treatment of first - episode schizophrenia

Name in Czech

Hladiny prolaktinu u pacientů s první atakou schizofrenie léčených risperidonem

Authors

ČEŠKOVÁ, Eva (203 Czech Republic, guarantor), Radovan PŘIKRYL (203 Czech Republic), Tomáš KAŠPÁREK (203 Czech Republic) and Marta ONDRUŠOVÁ (203 Czech Republic)

Edition

International Journal of Psychiatry in Clinical Practice, Paris, Cambridge University Press, Paris, 2004, 1461-1457

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

France

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.128

RIV identification code

RIV/00216224:14110/04:00025498

Organization unit

Faculty of Medicine

UT WoS

000220242100006

Keywords in English

first-episode schizophrenia; risperidone; treatment response; prolactin; correlation
Změněno: 19/6/2009 15:14, prof. MUDr. Eva Češková, CSc.

Abstract

V originále

Risperidone in an average dose lower than 4 mg significantly improved both positive and negative symptoms. Co-operating responders undergoing maintanance therapy showed a mild trend towards further long-term improvement. At the end of acute treatment the average elevation of PRL levels almost doubled the baseline value. There was a trend among responders to return to their initial values during long-term therapy. Three-quarters of the subject had hyperprolactinaemia at the end of acute treatment(44 days),and after 1 year about one-quarter had hyperprolactinaemia. No significant correlation between PRL change and PANSS score change was found.

In Czech

Článek pojednává o studii, která mapuje vliv léčby risperidonem u pacientů s první epizodou schizofrenie na hladinu prolaktinu v krvi