ČEŠKOVÁ, Eva, Radovan PŘIKRYL, Tomáš KAŠPÁREK and Marta ONDRUŠOVÁ. Prolaction levels in risperidone treatment of first - episode schizophrenia. International Journal of Psychiatry in Clinical Practice. Paris: Cambridge University Press, Paris, 2004, vol. 8, No 1, p. 31-36, 7 pp. ISSN 1461-1457.
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Basic information
Original name Prolaction levels in risperidone treatment of first - episode schizophrenia
Name in Czech Hladiny prolaktinu u pacientů s první atakou schizofrenie léčených risperidonem
Authors ČEŠKOVÁ, Eva (203 Czech Republic, guarantor), Radovan PŘIKRYL (203 Czech Republic), Tomáš KAŠPÁREK (203 Czech Republic) and Marta ONDRUŠOVÁ (203 Czech Republic).
Edition International Journal of Psychiatry in Clinical Practice, Paris, Cambridge University Press, Paris, 2004, 1461-1457.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher France
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 4.128
RIV identification code RIV/00216224:14110/04:00025498
Organization unit Faculty of Medicine
UT WoS 000220242100006
Keywords in English first-episode schizophrenia; risperidone; treatment response; prolactin; correlation
Tags correlation, first-episode schizophrenia, prolactin, risperidone, treatment response
Changed by Changed by: prof. MUDr. Eva Češková, CSc., učo 726. Changed: 19/6/2009 15:14.
Abstract
Risperidone in an average dose lower than 4 mg significantly improved both positive and negative symptoms. Co-operating responders undergoing maintanance therapy showed a mild trend towards further long-term improvement. At the end of acute treatment the average elevation of PRL levels almost doubled the baseline value. There was a trend among responders to return to their initial values during long-term therapy. Three-quarters of the subject had hyperprolactinaemia at the end of acute treatment(44 days),and after 1 year about one-quarter had hyperprolactinaemia. No significant correlation between PRL change and PANSS score change was found.
Abstract (in Czech)
Článek pojednává o studii, která mapuje vliv léčby risperidonem u pacientů s první epizodou schizofrenie na hladinu prolaktinu v krvi
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