HERMANOVÁ, Markéta, Zdeněk LUKÁŠ, Rudolf NENUTIL, Jan BRÁZDIL, Iva KROUPOVÁ, Leoš KŘEN, Marie PAZOURKOVÁ, Miloš RŮŽIČKA and Petr DÍTĚ. Amplification and overexpression of HER-2/neu in invasive ductal carcinomas of the pancreas and pancreatic intraepithelial neoplasms and the relationship to the expression of p21(WAF1/CIP1). Neoplasma. SLOVAKIA: VEDA, SLOVAK ACADEMY SCIENCES, 2004, 51/2004, No 2, p. 77-83. ISSN 0028-2685.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Amplification and overexpression of HER-2/neu in invasive ductal carcinomas of the pancreas and pancreatic intraepithelial neoplasms and the relationship to the expression of p21(WAF1/CIP1)
Name in Czech Amplifikace a overexprese HER-2/neu v invazivních duktálních karcinomech pankreatu a v pankreatických intraepiteliálních neoplaziích a jejich vztah k expresi p21(WAF1/CIP1)
Authors HERMANOVÁ, Markéta (203 Czech Republic, guarantor), Zdeněk LUKÁŠ (203 Czech Republic), Rudolf NENUTIL (203 Czech Republic), Jan BRÁZDIL (203 Czech Republic), Iva KROUPOVÁ (203 Czech Republic), Leoš KŘEN (203 Czech Republic), Marie PAZOURKOVÁ (203 Czech Republic), Miloš RŮŽIČKA (203 Czech Republic) and Petr DÍTĚ (203 Czech Republic).
Edition Neoplasma, SLOVAKIA, VEDA, SLOVAK ACADEMY SCIENCES, 2004, 0028-2685.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.822
RIV identification code RIV/00216224:14330/04:00018978
Organization unit Faculty of Informatics
UT WoS 000221307400002
Keywords in English adenocarcinoma; pancreas; HER-2/neu; p21; immunohistochemistry; FISH
Tags adenocarcinoma, FISH, HER-2/neu, Immunohistochemistry, p21, pancreas
Changed by Changed by: prof. MUDr. Markéta Hermanová, Ph.D., učo 1598. Changed: 22/6/2009 06:43.
Abstract
Overexpression of p21(WAF1/CIP1)seems to be HER-2/neu independent based on our results. Expression of HER-2/neu is growing according to grade of the ductal lesion and overexpression of HER-2/neu was demonstrated in 18% carcinomas. Two of 9 carcinomas with overexpression of HER-2/neu showed the amplification of HER-2/neu.
Abstract (in Czech)
Overexprese p21(WAF1/CIP1) je nezávislá na HER-2/neu dle našich výsledků. Exprese HER-2/neu narůstá podle gradu duktální léze a overexprese HER-2/neu byla prokázána v 18% karcinomů. Jen 2 z 9 karcinomů s overexpresí HER-2/neu měly amplifikaci tohoto genu.
PrintDisplayed: 25/4/2024 13:42